CLINICAL TRIALS AND OBSERVATIONS Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan
نویسندگان
چکیده
Masako Iwanaga,1,2 Toshiki Watanabe,3 Atae Utsunomiya,4 Akihiko Okayama,5 Kaoru Uchimaru,6 Ki-Ryang Koh,7 Masao Ogata,8 Hiroshi Kikuchi,9 Yasuko Sagara,10 Kimiharu Uozumi,11 Manabu Mochizuki,12 Kunihiro Tsukasaki,1 Yoshio Saburi,13 Masaomi Yamamura,14 Junji Tanaka,15 Yukiyoshi Moriuchi,16 Shigeo Hino,17 Shimeru Kamihira,18 and Kazunari Yamaguchi,19 for the Joint Study on Predisposing Factors of ATL Development investigators
منابع مشابه
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8 T cells, and disease severity in HTLV-1–associated myelopathy (HAM/TSP)
To investigate the role of viral expression in individuals infected with human T-cell lymphotropic virus type 1 (HTLV-1), a real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) of HTLV-1 tax messenger RNA (mRNA) using ABI Prism 7700 Sequence Detection System was developed. Using this system, the HTLV-1 tax mRNA load was compared with HTLV-1 proviral DNA load, HTLV-1 T...
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